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Discover the Healing Power of Hyperthermia Treatment
Have you ever noticed how your body creates a fever when you’re sick? That rise in temperature is not just a symptom – it’s a natural healing tool. Hyperthermia Treatment works in the same way: by safely raising your body’s temperature in a controlled medical setting, we activate your body’s powerful self-repair systems.
With IRATHERM® Whole-Body Hyperthermia, this process is precise, comfortable, and backed by decades of German medical innovation.
Hyperthermia Treatment gently warms your body to around 38.5–39.5°C, similar to a natural fever. This mild, safe heat:
- Improves blood circulation and oxygen delivery
- Activates the immune system (your body’s defense force)
- Reduces inflammation and chronic pain
- Helps detoxify the body
- Supports mental balance and relaxation
Think of it as giving your body a reset — boosting natural repair and energy at the cellular level.
Clinical studies with IRATHERM® show significant improvements for:
- Chronic Pain & Fibromyalgia – reduced pain, better sleep, more energy
- Hypertension – lower blood pressure and improved circulation
- Arthritis & Joint Conditions – reduced stiffness and inflammation
- Depression & Stress – improved mood and emotional resilience
- Immune Health – stronger defense against infections and chronic illness
- Cancer Support – enhances the effectiveness of chemotherapy and boosts immune response
- Anti-Aging & Wellness – promotes collagen production, muscle repair, and cellular rejuvenation
Even patients with Long-COVID have found relief through improved circulation and immune balance.
Not all heat therapies are the same. At Artisan Regenerative, our Hyperthermia Treatment uses the IRATHERM®1000M, a state-of-the-art whole-body hyperthermia system developed by the Von Ardenne Institute of Applied Medical Research in Germany. It represents over 40 years of clinical innovation in medically supervised hyperthermia therapy. IRATHERM® 1000M uses Water-Filtered Infrared-A (wIRA) technology – the same precision engineering trusted in aerospace and medical science.
IRATHERM® 1000M – Advanced Whole-Body Hyperthermia Technology
Unlike traditional heat therapies, the IRATHERM®1000M uses water-filtered infrared-A (wIRA) radiation — a form of heat that closely mimics the deep-penetrating part of natural sunlight. Water-filtering removes unwanted infrared-B and C wavelengths, allowing heat to safely and effectively penetrate tissues without overheating the skin surface.
Key technology highlights include:
- Deep, gentle warming: Quickly raises core body temperature to therapeutic levels (~39°C in ~45 min) in a controlled, comfortable way.
- Uniform whole-body irradiation: Six advanced radiators deliver consistent heat distribution.
- Open design for comfort: The patient lies on a comfortable net with unrestricted access — no enclosed chamber or claustrophobic experience.
- Real-time monitoring: Integrated software (IRAsoft®) tracks key data, including temperature and vital signs, throughout the session.
You simply lie comfortably while the system does the work. Most patients describe it as a deeply warming and relaxing experience.
How IRATHERM® Enhances Your Healing
Water-filtered infrared-A hyperthermia with the IRATHERM®1000M amplifies the body’s natural responses by gently elevating temperature in a way similar to a natural fever — a well-documented physiological signal that can stimulate healing pathways.
Benefits experienced by many patients include improved:
- Blood circulation and oxygen delivery
- Immune activation and detoxification processes
- Reduction in chronic pain and inflammation
- Energy levels, sleep quality, and mental balance
While individual outcomes vary, IRATHERM®’s technology supports both wellness and clinical applications, from chronic pain relief and cardiovascular support to adjunctive care in integrative oncology.
IRATHERM 1000M Life in evolution with hyperthermia : Improving health and quality of life.
Von Ardenne | Applied Biomedical Technologies | IRATHERM Whole-Body Hyperthermia
Hyperthermia therapy is especially helpful for those struggling with:
Pain & Musculoskeletal Conditions
- Muscle tension
- Chronic back pain
- Chronic pain or fatigue
- Neuralgia
- Fibromyalgia
- Ankylosing spondylitis
- Rheumatic diseases
Inflammatory & Autoimmune Conditions
- Chronic and subacute inflammation
- Autoimmune conditions
- Systemic scleroderma
Respiratory & Allergic Conditions
- Bronchial asthma
- Allergic conditions (e.g. hay fever, neurodermatitis)
Cardiovascular & Metabolic Support
- Cardiovascular issues
- Blood pressure regulation
- Metabolic support
- Detoxification support
Oncology Support
- Cancer (as an adjunct treatment)
- Adjunct to chemotherapy
- Oncological pain relief
- Immune system support
Neurological, Stress & Mental Wellbeing
- Stress, burnout, or depression
- Post-COVID symptoms
Skin, Recovery & Wellness
- Skin concerns (inflammation, scars, anti-aging)
- Post-exercise recovery
- Weight management
It’s also chosen by many patients who want to stay healthy, age gracefully, and strengthen their natural resilience.
- Relax – You’ll lie down comfortably in the IRATHERM® system.
- Gentle Warming – Your core body temperature is slowly raised.
- Healing Phase – The therapeutic temperature is maintained.
- Cool Down – Your body is brought back to normal temperature.
Sessions typically last 60–90 minutes. Many patients feel refreshed, lighter, and more energetic afterward.
Whether you’re seeking relief from a chronic condition or simply want to boost your body’s natural resilience, Hyperthermia Therapy with IRATHERM® can help.
📞 Contact us today to learn more or schedule your first session.
Whole-Body Hyperthermia for Fibromyalgia
A science-backed therapy for lasting pain relief
Fibromyalgia is one of the most challenging chronic pain conditions to treat — affecting sleep, mood, and quality of life alongside widespread musculoskeletal pain. At Artisan Clinic, we offer Whole-Body Hyperthermia (WBH) using the Iratherm® 1000, a medically registered device that uses water-filtered infrared-A (wIRA) radiation to gently raise your core body temperature into a controlled, fever-like range.
This is not a sauna. It is a precision medical therapy — and there is a growing body of peer-reviewed evidence behind it.
How It Works
The Iratherm® 1000 uses water-filtered infrared-A light to warm the body from the outside in, bringing your core temperature to approximately 38.5–38.7°C — similar to a mild natural fever. This therapeutic warmth is held for a short plateau period, triggering your body's natural pain-dampening responses.
For fibromyalgia, we use the mild hyperthermia protocol — not the higher-dose oncological range. Sessions are comfortable, monitored throughout, and typically last 60 minutes.
What the Research Shows
Multiple peer-reviewed studies, conducted over nearly three decades across several German medical centres, have consistently found that mild wIRA whole-body hyperthermia reduces fibromyalgia pain and is well tolerated.
The strongest evidence to date:
Langhorst et al., Journal of Clinical Medicine 2023 — the only sham-controlled randomised trial of this therapy in fibromyalgia. In 41 patients, six WBH sessions over three weeks produced:
- Significantly lower pain scores at 4 weeks (p = 0.015)
- Benefits that persisted at 7 months (p = 0.002)
- No withdrawals due to side effects
Brockow et al., Clinical Journal of Pain 2007 — a randomised controlled trial in 139 inpatients found that adding WBH to a standard rehabilitation programme produced a moderate additional reduction in pain (Cohen's d ≈ 0.60) compared to rehabilitation alone.
Walz et al., Schmerz 2013 — a three-arm controlled trial found pain benefits persisting to 6 months, and notably found that once-weekly treatment outperformed twice-weekly — suggesting a lower-frequency schedule may be optimal.
The honest picture: the evidence is promising and consistently positive, the therapy is well tolerated, and the best results come when WBH is used alongside your existing care — not as a replacement for it.
What a Course of Treatment Looks Like
Sessions: 6 outpatient sessions
Schedule: Over 3 weeks (at least one rest day between sessions)
Duration: ~60 minutes per session
Target temperature: 38.5–38.7°C core
Monitoring: Core temperature, pulse and oxygen levels throughout
Hydration: You will be asked to stay well hydrated
Is It Right for You?
WBH is generally well tolerated. However, it is not suitable for everyone. We will always complete a thorough screening before recommending this therapy.
This therapy may not be appropriate if you have:
- A current febrile illness or core temperature above 37.5°C
- Significant cardiovascular disease (e.g. heart failure)
- Severe comorbidities (somatic or psychiatric)
- Pregnancy
Please inform us of all medications you take, particularly those affecting fluid balance or thermoregulation.
Device & Regulatory Status
The Iratherm® 1000M is a registered medical device in the EU, Singapore, and Malaysia.
Jurisdiction | Status
European Union | CE-marked, Class IIa
Singapore (HSA/SMDR) | Registered Class B — Reg. no. DE0506482
Malaysia (MDA) | Registered Class B — Reg. no. GB6786221-55575
The device is registered for whole-body hyperthermia and relief of muscle fatigue, stiffness and pain. As with most physical therapies, regulatory approvals are for the device and its method — not a fibromyalgia-specific disease indication.
Frequently Asked Questions
Is this the same as a sauna or infrared sauna?
No. The Iratherm® 1000 uses a specific, medically calibrated water-filtered infrared-A wavelength with precise temperature monitoring. It is a Class B registered medical device, distinct from consumer wellness products.
How soon will I feel a difference?
Research suggests some patients notice improvement during or shortly after the first sessions, while for others benefit builds over the course of treatment and beyond. One study found the duration of time held at target temperature may predict how long-lasting the relief is.
Can I continue my other treatments?
Yes — and we encourage it. The evidence supports WBH as a complement to your existing care, not a replacement.
Are there side effects?
Side effects are mostly short-lived physiological responses to warmth — similar to what you might experience after gentle exercise. In the only sham-controlled clinical trial, no patients withdrew due to side effects.
This page is for general information only and does not constitute medical advice. Suitability for treatment is determined on an individual basis by your clinician. Speak to our team to find out whether this therapy is appropriate for you.
Whole-Body Hyperthermia with the Iratherm® 1000 (wIRA)in Fibromyalgia
Long COVID Patient Information
Application of Whole-Body Hyperthermia to Support"Long-COVID" (POST-COVID-19) Rehabilitation
Jost Langhorst, Anna K. Koch, Christina Kehm, Özlem Öznur, Harald Engler and Winfried Häuser
Mild Water-Filtered Infrared-A Whole-Body Hyperthermia Reduces Pain in Patients with Fibromyalgia Syndrome—A Randomized Sham-Controlled Trial
Özlem Öznur, Christoph Schlee, Sandra Utz and Jost Langhorst
Investigating the Influential Factors of Mild Water-Filtered Infrared-A Whole-Body Hyperthermia for Pain Relief in Fibromyalgia: A Mixed-Methods Approach Focusing on Predictors and Patient Perspectives
MA Wei-ping, ZHU Bing, WANG Wen, KANG Ning-chao, MA Jun-ping, SUN Jin-zi, SHAN Su-ying
A comparative study on the effect of water filtered infrared-a irradiation and common infrared irradiation in the treatment of lumbar disc herniation
John Foerster, Susanne Fleischanderl, Stefan Wittstock, Annegret Storch, Hans Meffert, Gabriela Riemekasten, w and Margitta Worm
Infrared-Mediated Hyperthermia Is Effective in the Treatment of Scleroderma-Associated Raynaud’s Phenomenon
B. Meffert, O. Hochmuth, M.Steiner, H.-P.Scharf, H.Meffert
Effects of a multiple mild infra-red-A induced hyperthermia on central and peripheral pulse waves in hypertensive patients
Barbara Hochecker, Katja Matt, Melanie Scherer, Alica Meßmer, Alexander von Ardenne and Jörg Bergemann
Heat vs. Fatigue: Hyperthermia as a Possible Treatment Optionfor Myalgic Encephalomyelitis/Chronic Fatigue Syndrome(ME/CFS)
FABIAN KOCKELMANN, URS GIGER-PABST, MEHDI OUAISSI, PETRU BUCUR, SARAH BARBEY, ALEXANDER VON ARDENNE and JÜRGEN ZIEREN
First Clinical Safety and Feasibility Data of Whole-body Hyperthermia Pressurized Intraperitoneal Aerosol Chemotherapy (WBH-PIPAC) for Peritoneal Surface Malignancies
Clemens W. Janssen, PhD; Christopher A. Lowry, PhD; Matthias R. Mehl, PhD; John J. B. Allen, PhD;Kimberly L. Kelly, MPA; Danielle E. Gartner, BA; Angelica Medrano, BA; Tommy K. Begay, PhD;Kelly Rentscher, MA; Joshua J. White, BS; Andrew Fridman, BS; Levi J. Roberts, BA; Megan L. Robbins, PhD;Kay-u Hanusch, MSc; Steven P. Cole, PhD; Charles L. Raison, MD
Whole-Body Hyperthermia for the Treatmentof Major Depressive Disorder : A Randomized Clinical Trial
Michael C. Flux, David G. Smith, John J. B. Allen, Matthias R. Mehl, Andi Medrano, Tommy K. Begay, Brandon H. Middlemist, Brandon M. Marquart, Steven P. Cole, Christina J. Sauder, Christopher A. Lowry, Charles L. Raison
Association of plasma cytokines and antidepressant response following mild-intensity whole-body hyperthermia in major depressive disorder
Alex T. Von Schulze, Fengyan Deng, Jill K. Morris, and Paige C. Geiger
Heat therapy: possible benefits for cognitive function and the aging brain
Ana Belen Lopez‑Rodriguez, Carol L. Murray, John Kealy, Clodagh Towns, Andrew Roche, Arshed Nazmi, Michelle Doran, John P. Lowry and Colm Cunningham
Hyperthermia elevates brain temperatureand improves behavioural signs in animal models of autism spectrum disorder
Alexander von Ardenne
Technique of Whole-Body Hyperthermia and the Fibromyalgia Syndrome–first Controlled Clinical Trials
Gerrit Günther (QMR)
Clinical Evaluation IRATHERM1000M of Von Ardenne Institute of Applied Medical Research GmbH
Our Mission
To empower individuals to live longer, healthier lives, while embracing a gradual, lifestyle-friendly approach. By bridging cutting-edge research with practical solutions, we aim to inspire a global community to take control of their aging journey—today, not tomorrow.
How Can We Help
At Artisan Regenerative Centre, we offer a proactive approach to aging, focusing on science-based therapies that align with your lifestyle. Whether you’re looking for a gradual, less invasive path or exploring cutting-edge solutions, we can help you take the right steps toward better health and longevity.
